injectable

Injectable scaffold to heal brain damage from stroke

Stroke, the main cause of adult disability, leaves a hole, or cavity, in the brain, destroying tissue and cell networks. Physical therapy is the only approved treatment for stroke, relying on the brain’s ability to rewire itself to regain function without healing the damaged tissue. This highlights an opportunity for regenerative medicine to improve healing and long term outcomes for stroke patients. A possible solution to stroke therapy shortcomings Transplanting neural stem cells into the damaged tissue has not yet been able…

Cryogels with Sandeep Koshy

Hydrogels have been used successfully in many tissue engineering applications.  However, because they are inherently soft materials, it is not always easy to get the large, interconnected pore network that enhances cell behavior and allows neovascularization of implants.  Many techniques have been developed to try and create pore networks after the gelling process completes, like using salt or sugar porogens.  But porogens must be removed to create the pore network, and the removal process has always been the Achilles heel…

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